What is the Function of Chondroitin Sulfate
Chondroitin sulfate is widely distributed in human and animal cartilage tissues. Its medicinal preparations mainly contain chondroitin sulfate A and chondroitin sulfate C isomers. Chondroitin sulfate content in the cartilage of different species and ages of animals is different. Its pharmacological effects are as follows:
1. The main way of medical application is to treat joint diseases as a drug, combined with glucosamine, with analgesic effect, promote cartilage regeneration, can fundamentally improve joint problems.
Randomized placebo-controlled clinical trials have shown that chondroitin sulfate can reduce pain in patients with osteoarthritis, improve joint function, reduce joint swelling and fluid accumulation, and prevent space narrowing between knee and hand joints. It provides a cushioning effect to ease the impact and friction during movement and can inhale water into the proteoglycan molecule, thicken the cartilage and increase the amount of synovial fluid in the joint. One of the important functions of chondroitin is to act as a delivery pipeline to deliver important oxygen and nutrients to the joints, helping to remove waste from the joints, while removing carbon dioxide and waste. Since there is no blood supply to the articular cartilage, all the oxygenation, nourishment and lubrication effects come from synovial fluid.
2. It can increase the biosynthesis of messenger RNA and DNA and promote cell metabolism.
3, Low anticoagulant activity. Chondroitin sulfate has a mild anticoagulant effect, and each LMG of chondroitin sulfate A is equivalent to 0.45U heparin in anticoagulant activity. This anticoagulant activity does not depend on antithrombin III, but on the fibrinogen system.
4. It can be used as an additive in health food and food. It can enhance human body constitution and resist bacteria, beauty, anti-aging and so on. Improve hearing and skin dryness. It can inhibit the absorption of lipids and glucose by the small intestine in order to achieve weight loss.
Long-term clinical applications have shown that lipids such as fat deposited on arterial and venous walls can be effectively removed or reduced, significantly reducing plasma cholesterol, thereby preventing the formation of atherosclerosis.
Chondroitin sulfate is used to treat neuralgia, migraine, arthralgia, arthritis, scapular joint pain, postoperative pain after abdominal surgery, etc.
Prevention and treatment of streptomycin-induced hearing impairment and various noise-induced hearing difficulties, tinnitus, etc., the effect is significant.
It has auxiliary therapeutic effects on chronic nephritis, chronic hepatitis, keratitis, and corneal ulcer.